USE AND IMPORTANT SAFETY INFORMATION2

USE2

VICODIN® 5 mg/300 mg, VICODIN ES® 7.5 mg/300 mg, and VICODIN HP® 10 mg/300 mg (hydrocodone bitartrate and acetaminophen) tablets, USP are used for the relief of moderate to moderately severe pain. VICODIN, VICODIN ES, and VICODIN HP contain two different ingredients: hydrocodone (an opioid pain medicine) and acetaminophen (a non-aspirin pain medicine).

IMPORTANT SAFETY INFORMATION2

Warning for liver damage: One ingredient in this product is acetaminophen. Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.